Lippincott's Illustrated Reviews: Pharmacology, 4th Edition

Lippincott's Illustrated Reviews: Pharmacology, 4th Edition

Lippincott's Illustrated Reviews: Pharmacology, 4th Edition
By Richard A Harvey, Pamela C. Champe, Richard Finkel, Luigi X. Cubeddu
Publisher: Lippincott Williams & Wilkins; Fourth Edition edition | 2008 | 560 Pages | ISBN: 0781771552 | PDF | 51.43 MB

Lippincott's Illustrated Reviews: Pharmacology, Fourth Edition enables rapid review and assimilation of large amounts of complex information about the essentials of medical pharmacology. Clear, sequential pictures of mechanisms of action actually show students how drugs work, instead of just telling them. As in previous editions, the book features an outline format, over 500 full-color illustrations, cross-references to other volumes in the series, and over 125 review questions. Content has been thoroughly updated, and a new chapter covers toxicology. New to this edition will be a companion Website containing all of the illustrations, fully searchable text, and an interactive question bank.

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Harry G. Brittain, "Polymorphism in Pharmaceutical Solids, Second Edition"

Polymorphism in Pharmaceutical Solids, Second Edition

Harry G. Brittain, "Polymorphism in Pharmaceutical Solids, Second Edition"
Informa Healthcare | 2009 | ISBN: 1420073214 | 656 pages | PDF | 4,9 MB

Using clear and practical examples, Polymorphism in Pharmaceutical Solids, Second Edition presents a complete examination of polymorphic behavior in pharmaceutical development.

Ideal for pharmaceutical development scientists and graduate students in pharmaceutical science, this updated edition includes:

NEW CHAPTERS - on the latest developments and methods in the field that give pharmaceutical development scientists the up-to-date information they need to successfully implement new drug development techniques and methods

EXPERT EDITORSHIP - from Dr. Harry G. Brittain, whose vast experience and knowledge of the pharmaceutical industry provides readers with the authoritative advice they need and trust

COMPREHENSIVE CONTENT - that includes information appropriate for all levels of expertise in the field, from experienced pharmaceutical scientists to graduate students in physical pharmacy

200 HIGH QUALITY ILLUSTRATIONS - that present readers with a visual blueprint to the methods and techniques involved in polymorphism and solvatomorphism

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Comprehensive Pharmacy Review

Comprehensive Pharmacy Review

Comprehensive Pharmacy Review
Lippincott Williams & Wilkins | 2009-01-01 | ISBN: 158255711X | 1472 pages | PDF | 13 MB

Completely revised to reflect current progress in pharmacy education and practice, the Seventh Edition of this best-selling review guide is indispensable for all pharmacy students, from the first year of professional courses to preparation for the NAPLEX examination. A wide range of topics central to the study of pharmacy--chemistry, pharmaceutics, pharmacology, pharmacy practice, drug therapy--are organized to parallel the pharmacy curriculum and presented in outline form for easy use. Comprehensive Pharmacy Review may be used as a quick review or preview of essential topics by a diverse group of readers, including matriculation pharmacy students, instructors and preceptors, professional pharmacists, and foreign pharmacy graduates.

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Handbook of Solubility Data for Pharmaceuticals

Handbook of Solubility Data for Pharmaceuticals

Abolghasem Jouyban, "Handbook of Solubility Data for Pharmaceuticals"

CRC 2009 | ISBN-10: 1439804850 | 552 Pages | PDF | 1,5 MB

Aqueous solubility is one of the major challenges in the early stages of drug discovery. One of the most common and effective methods for enhancing solubility is the addition of an organic solvent to the aqueous solution. Along with an introduction to cosolvency models, the Handbook of Solubility Data for Pharmaceuticals provides an extensive database of solubility for pharmaceuticals in mono solvents and binary solvents. Aqueous solubility data can be found in the Handbook of Aqueous Solubility Data by Samuel Yalkowsky and Yan He. Visit www.crcpress.com for more information.

In addition to the experimental efforts to measure the solubility of drugs in mono and mixed solvents, this book discusses the advantages and limitations of a number of mathematical models used to predict the solubility in mono or mixed solvent systems. It covers the pharmaceutical cosolvents and other organic solvents that are used in syntheses, separations, and other pharmaceutical processes. The solutes featured include the available data for official drugs, drug candidates, precursors of drugs, metabolites, and degradation products of pharmaceuticals. The author also presents the solubilities of amino acids since they play an important role in peptide drug properties.

Collecting drug solubilities in various cosolvents, this time-saving handbook includes the mixtures and model constants needed to predict undetermined solubilities. It describes mathematical models that enable data to be derived and provides estimates on how drugs are likely to behave in a given cosolvent. A software program and associated user manual are available on the author’s website.

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Solving Problems in Food Engineering

Solving Problems in Food Engineering

* Allows those with little or no background in engineering to grapple with food engineering problems

* Includes supplemental text that covers the basics of food engineering problem solving

* Carefully graded practice problems progress from easy to complex

Solving Problems in Food Engineering is a step by step workbook intended to enhance students' understanding of complicated concepts and to help them practice solving food engineering problems. The book covers problems in fluid flow, heat transfer, mass transfer, and the most common unit operations that have applications in food processing, such as thermal processing, cooling and freezing, evaporation, psychrometrics and drying. Included are theoretical questions in the form of true or false, solved problems, semi-solved problems, and problems solved using a computer. The semi-solved problems guide students through the solution. Some of the problems progress from elementary level increasing difficulty so that the book is useful to food science as well as food engineering students.

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ABC Transporters and Multidrug Resistance

ABC Transporters and Multidrug Resistance

A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance

ATP-binding cassette transporter genes (ABC transporters) are known to play a crucial role in the development of multidrug resistance (MDR). MDR is the ability of pathologic cells, such as tumors, to withstand chemicals designed to target and destroy such cells. In MDR, patients who are on medication eventually develop resistance to not only the drug they are taking, but to several different types of drugs.

ABC Transporters and Multidrug Resistance offers an essential resource for pharmaceutical researchers who are working discover drugs to counteract multidrug resistance in diseases such as cancer. In one comprehensive volume, this book contains a collection of the most current knowledge on the involvement of ABC transporters in drug transport and resistance.

This comprehensive volume provides an overview on the description of the structure, the genome, normal tissue expression, physiological aspect, and mechanism of action of the ABC protein. The expert contributors explore the expression, detection, and implications of ABC proteins in hematological malignancies and solid tumors and ABC proteins and pathogenic microorganisms. This volume also explains MDR modulation through inhibition of ABC transporters and the design of inhibitors and mechanism of action. In addition, the book offers essential information on the biological and clinical aspect of multidrug resistance.

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HPLC for Pharmaceutical Scientists Yuri V. Kazakevich, Rosario LoBrutto

Hplc For Pharmaceutical Scientists (2007; Wiley)

HPLC for Pharmaceutical Scientists
Yuri V. Kazakevich, Rosario LoBrutto

Publisher: Wiley
ISBN: 978-0-471-68162-5
Pages: 1136
Release date: January 2007

HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry.

In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided.

This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development.

The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.

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